Sexual Health peptides

4 peptides tagged sexual health. Each page carries the dosing reference, mechanism, evidence grade and references.

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  • HCG

    Urine-derived placental glycoprotein acting on the LH receptor; labeled IM as Pregnyl and Novarel for cryptorchidism, male hypogonadotropic hypogonadism and ovulation induction. TRT use is off-label.

    Evidence: Clinical

  • Kisspeptin-10

    Ten-residue C-terminal kisspeptin fragment that activates KISS1R (GPR54); IV doses raised LH and LH pulse frequency in small human studies. Not approved anywhere; on FDA's 503A safety list.

    Evidence: Preclinical

  • Melanotan II

    Synthetic cyclic alpha-MSH(4-10) analog that binds MC1, MC3, MC4 and MC5 receptors; small 1990s human trials found skin darkening and erections. Never approved.

    Evidence: Clinical

  • PT-141

    Bremelanotide, a cyclic melanocortin receptor agonist and close analog of melanotan II; approved by the FDA in 2019 as Vyleesi (1.75 mg SC) for acquired HSDD in premenopausal women.

    Evidence: Clinical

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