Palmitoyl Dipeptide-6

Evidence: Anecdotal

PeptideLab is an educational platform for learning about peptides. The information here is for educational and research purposes only. It is not medical advice, diagnosis, or treatment, and PeptideLab does not claim to diagnose, treat, cure, or prevent any disease or health condition. Many peptides discussed have not been approved for human use by the FDA or other regulatory bodies. Consult a qualified healthcare professional before making any health-related decision.

Overview

Lipidated cosmetic peptide sold under a name whose exact structure could not be confirmed; no peer-reviewed study of any kind was found.

The record name matches no single confirmed molecule. Vendors list 'Palmitoyl Dipeptide-6' with CAS 794590-34-4, which PubChem files as palmitoyl-Lys-Val-diaminobutyrate trifluoroacetate under the name palmitoyl dipeptide-5 diaminohydroxybutyrate; a related ingredient, palmitoyl dipeptide-6 diaminohydroxybutyrate, appears on cosmetic ingredient lists. The old record gave Pal-Val-Leu, which matches none of these. No peer-reviewed study of any of these molecules was found in PubMed, so every functional claim rests on supplier literature.

Benefits

Supplier-reported firmness effects only; no peer-reviewed data in any model

Dosing reference

Research dose: Topical by supplier framing; no published concentration or study.

Topical cosmetic ingredient. No peer-reviewed study in any model; supplier data only.

Mechanism

Unknown. Supplier material describes retinoid-like or matrix-stimulating activity, but no peer-reviewed study of this ingredient exists, and the molecule itself is ambiguous. Claims of collagen, elastin and fibronectin upregulation, matrix crosslinking and MMP inhibition have no published source.

Evidence

Anecdotal: no peer-reviewed data

No peer-reviewed study of palmitoyl dipeptide-6 in cells, animals or humans was found in PubMed
Human-trial status: none; all claims come from supplier literature, and the molecule's structure could not be confirmed

Side effects

No safety data in any species. Commonly reported (anecdotal): mild irritation or redness.

Storage

Storage: Room temperature, away from light
Lyophilized: 2 years at room temp
Reconstituted: N/A (ready to use)

Pharmacology

Half-life: No published pharmacokinetic data in any species
Bioavailability: Not measured in any species